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Funding Open access funding provided by The Science, Technology & Innovation Funding Authority (STDF) in cooperation with The Egyptian Knowledge Bank (EKB)

Despite its benefits in blood sugar control and weight management, the cost of semaglutide based medications may present economic hurdles for certain individuals and healthcare systems

According to Celltrion, Steqeyma was approved based in part on the findings of a Phase III study in plaque psoriasis, which demonstrated that the biosimilar had no clinically meaningful differences versus Stelara in terms of efficacy or safety

Hypothalamic carnitine palmitoyltransferase is involved, along with fatty acid synthase in the regulation of the melanocortin system, and since many factors including TNF- and IL-1 inhibit fatty acid oxidation [88, 89], it is conceivable that l-carnitine supplementation may affect energy intake in cachectic patients